ALZEPIL. 5 mg. 28 tablets
This medicine can improve memory and thinking.
ALZEPIL. 5 mg. 28 tablets
What Alzepil and what it is used?
Alzepil ( donepezilov hydrochloride ) belongs to the group of drugs known as acetylcholinesterase inhibitors , It is used to treat the symptoms of dementia in patients who have been diagnosed with mild to moderately severe Alzheimer's disease .
This medicine can improve memory and thinking .
2 . What you should know before taking Alzepil ?
Do not take Alzepil :
- If you are allergic to donepezilov hydrochloride to similar medicines (called piperidine derivatives ) or any of the other ingredients of this medicine (listed in Section 6) .
Warnings and Precautions
Talk to your doctor before taking Alzepil .
If you have any of the following diseases / conditions you should tell your doctor before taking this medicine:
- If you have heart disease ( irregular heartbeat , heart block , for example ) ( donepezil can slow heart rate ), if you have ever had a stomach ulcer or duodenal ulcer , or if you take both anti-inflammatory drugs (NSAIDs ) ;
- If you have difficulty urinating ;
- If you have had fainting ( donepezil can induce a seizure ) or syncope ;
- If you suffer from asthma or other long-term lung disease , if you have severe liver disease ;
- If you have ever had extrapyramidal symptoms ( uncontrolled movements of the body or face) .
- If you have an operation that requires general anesthesia, you should inform your doctor and anesthetist that you are taking Alzepil .
Children and adolescents
For use in adult patients.
Other medicines and Alzepil
Tell your doctor if you are taking , have recently taken or taking other medicines, including medicines obtained without a prescription.
Tell your doctor if you are taking any other medicines, especially : painkillers and anti-inflammatory ( NSAID ) for the treatment of arthritis;
- Antibiotics , such as rifampicin and erigromitsin ;
- Antifungal medicines (medicines that kill fungi or inhibit their growth ) , such as ketoconazole and itraconazole ;
- Muscle relaxants ;
- Antidepressants such as fluoxetine ;
- Anticonvulsants such as phenytoin or carbamazepine ;
- Medicines for heart disease;
- Certain medications to lower blood pressure (beta -blockers ), other drugs which act in the same manner as donepezil ( such as galantamine, or rivastigmine ) as well as certain drugs for diarrhea , Parkinson's disease , or asthma .
Alzepil with food, drinks and alcohol
Take the tablets with a glass of water at bedtime . Alzepil can be taken without regard to food , as it does not affect the action of the drug.
Do not take any alcohol during treatment with donepezil , because alcohol can reduce its effectiveness.
Pregnancy, lactation and fertility
Alzepil should not be used during pregnancy unless clearly necessary ( prescribed by your doctor) because there are limited data on the effects on these patients.
Women taking donepezil should not breast feed .
Driving and using machines
Your illness may lead to a deterioration of the ability to drive and use machines. Your medicine may cause fatigue, dizziness and muscle spasm , mainly early in treatment or when increasing the dose . Therefore, the treating doctor will assess your ability to continue to drive or operate machinery.
Your doctor will decide which dose individually when you can drive or operate machinery.
3 . How to take Alzepil ?
Always take Alzepil exactly as your doctor tells you . If you are not sure, ask your doctor or pharmacist.
Tell your doctor or pharmacist name of the person who cares for you. It will help you take your medicine as prescribed .
Take your tablet Alzepil orally ( with a glass of water) at bedtime . Alzepil can be taken without regard to food as it does not affect the performance of Alzepil .
The recommended starting dose is 5 mg once daily. After one month , your doctor may prescribe you to take 10 mg in the evening . The maximum recommended daily dose is 10 mg.
You should always follow your doctor's instructions about how and when taking your medicine . Do not change the dose yourself, without consulting with your doctor and do not stop taking the tablets unless instructed by your doctor .
Your doctor will tell you how long to take the tablets. I'll visit from time to time to monitor your treatment and evaluate the signs .
This medicine is not recommended for use in children and adolescents (under 18 years).
If you take more dose Alzepil
Do not take more than 10 mg a day. Immediately contact your doctor if you take more than prescribed . If you can not tell immediately contact the nearest unit for emergency care.
Take the tablets and the pack with you to the hospital to the doctor to find out what you have taken.
If you forget to take Alzepil
Do not take a double dose to make up for a missed dose as this can not be done , but run the risk of overdose. Continuing treatment as prescribed.
If you forget to take your medicine for more than one week , tell your doctor before you start taking it again. If you stop taking Alzepil
If stopping treatment, a gradual reduction of the beneficial effects of Alzepil . It is not a reversion signs of disease after abrupt discontinuation of the drug.
Do not stop treatment without first discussing it with your doctor even if you feel better.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4 . Possible side effects
Like all medicines » this medicine can cause side effects, although not everybody gets them
You should immediately contact your doctor if you notice any of these side effects, as it is possible to need emergency treatment.
• High fever with stiff muscles , sweating or a lowered level of consciousness ( a disorder that is called Devroleptichen malignant syndrome ').
Contact your doctor if you experience any of these side effects or if they cause you discomfort :
Very common (1-10 of 10):
Diarrhea , nausea ( feeling sick) , vomiting .
Common ( 1-10 of 100):
Common cold , anorexia (loss of appetite) , hallucinations , agitation, aggressive behavior ( cases of hallucinations, agitation and aggressive behavior were detected in dose reduction or discontinuation of Alzepil ) , syncope ( fainting ), dizziness , insomnia (sleeplessness ) vomiting, abdominal discomfort, rash , muscle cramps , urinary incontinence , fatigue , pain , accident,
Uncommon (less than 1 in 100 patients):
Convulsions, bradycardia ( slow heart rate ) , bleeding in the digestive tract , stomach ulcer or duodenal abnormal results from laboratory studies ( slight increase in serum concentrations of muscle creatine kinase) .
Rare ( less than 1 in 1000 patients):
Extrapyramidal symptoms ( tremor, rigidity go uncontrollable movements of the muscles of the face, tongue or lips ) , sinus - atrial block , irregular heartbeat ( cardiac arrest ) , abnormal liver function, including hepatitis ( liver infection ) .
If you get any side effects , tell your doctor. This includes all listed in this leaflet .
5 . How to store Alzepil ?
This medicinal product does not require any special storage conditions . Keep out of reach of children .
Do not use this medicine after the expiry date stated on the packaging ( MM GTTT ) . The expiry date refers to the last day of that month.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.
6 . Package Contents and more information
What does Alzepil ?
- The active ingredient is a hydrochloride donepezilov - Each tablet contains 5 mg or 10 mg;
- The other ingredients are: core : microcrystalline cellulose , hydroxypropylcellulose, magnesium stearate, film- coating: Opadry Y- 1-7000 White: hypromellose, tiganov dioxide (E 171 ) , macrogol 400 .
Alzepil looks like and contents of the pack ?
5 mg: White or off-white, free or nearly odorless , round, biconvex film-coated tablets with a stylized " E 3 81 " on one side .
10 mg: White or off-white, free or nearly odorless , round, biconvex film-coated tablets with a stylized " E 382 " on one side .
Packing: 28 or 56 film-coated tablets are placed on the blister in a cardboard box.