AKINESTAT. 2 mg. 50 tablets

AKINESTAT. 2 mg. 50 tablets
€ 15.00
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Akinestat belongs to a group of drugs known as anticholinergic drugs, i.e. those which antagonize or block the action of acetylcholine. They have a central action and mild peripheral effects. As a result of blocking the cholinergic receptors, and biperiden alleviates eliminates the symptoms of Parkinsonism. 

AKINESTAT. 2 mg. 50 tablets

 
 
Ingredients:
drug
Each tablet contains 2mg Biperiden hydrochloride.
 
 
Excipients:
Magnesium stearate; lactose monohydrate ; microcrystalline cellulose .
 
Formulation and packaging
• Blister (A1/PVC)
50 tablets (5 blister of 10 tablets in blister) per carton.
 
 
Pharmacotherapeutic group
Akinestat belongs to a group of drugs known as anticholinergic drugs , i.e. those which antagonize or block the action of acetylcholine . They have a central action and mild peripheral effects. As a result of blocking the cholinergic receptors , and biperiden alleviates eliminates the symptoms of Parkinsonism .
 
Indications for treatment
Akinestat administered alone to treat Parkinson's syndrome , especially in muscle rigidity and tremor.Prilagan in combination , it enhances the therapeutic effect of the El- Dopa . Akinestat finds application in the treatment of extrapyramidal effects, such as acute dystonia , akathisia ( a condition characterized by uncontrolled movements of the muscles) , or Parkinson's syndrome induced by treatment with neuroleptics ( antipsychotic drugs ) , or reactions of other origin
 
Contraindications :
Akinestat is contraindicated in cases of hypersensitivity to biperiden or any of the excipients , myasthenia gravis (a disease characterized by muscle weakness ) , untreated glaucoma , obstruction of the gastrointestinal tract , urinary tract obstruction , paralysis of the gut or lack of intestinal tone , reflux oesophagitis , ulcerative colitis, toxic megacolon or ( extension of the large intestine) , unstable cardiovascular condition in an acute kravozaguba.Otnositelno contraindication prostatic hypertrophy with retention of residual urine and conditions that may lead to life-threatening tachycardias .
 
Special precautions for use :
Akinestat should be used with caution in the elderly , especially those with organic brain changes in patients with prostate enlargement , tachyarrhythmia ( heart rate with arrhythmia) , congestive heart failure, angina, high blood pressure, ileostomy / colostomy ( surgical clearance artificial anus by coupling of the ileum to an opening in the abdominal wall ) . . Safety and effect in children has not been established.
 
Interactions :
With concomitant administration of biperiden , and drugs having secondary anticholinergic effects (eg some narcotic analgesics such as meperidine, phenothiazines and other antipsychotics , tricyclic antidepressants, certain antiarrhythmics as hinidinovi salts or antihistamines ) may occur sindrom.Ednovremennata central anticholinergic use Akinestat and levodopa medication is administered to reduce the dose of the past and avoid complications such as ??????????.????????????????? can enhance the effect of peptidin CNS . When using Akinestat can increase the effect of the alcohol. Treatment with Akinestat can prevent the action of metoclopramide and other substances having a similar effect on the gastrointestinal tract .
 
Special warnings :
There have been isolated cases of mental confusion , elation , anxiety or inappropriate behavior in susceptible patients taking properly prescribed treatment with anticholinergic drugs. Should be devoid of alokohol during treatment with biperiden . Akinestat can cause neuromuscular blockade manifested by weakness and paralysis.
U lactation Pregnancy
To avoid the use of biperiden during pregnancy . The drug is excreted in the breast milk and may cause unpleasant anticholinergic effects in the infant, which is why it is recommended that nursing be discontinued. Akinestat can be used during pregnancy and lactation unless its use is extremely nalozhitelna.Efekti on ability to drive and use machines Medikametat strongly influence the psychophysical abilities. Driving motor vehicles or operating machinery shall be prohibited during the treatment course with Akinestat .
 
Dosage and administration :
The dose and duration of therapy is determined by the attending physician . Treatment begins with gradually increasing doses until the optimum dose (usually 2-16 mg for most patients , divided into 3-4 separate doses) . Akinestat tablets taken with fluid , preferably after hranene.Lechenieto should be terminated gradually reduce dozata.Pri elderly patients , especially those with pre-existing brain damage should be carefully dozirane.Opitat with biperiden in children is limited .
overdose
Biperiden overdose resulting in symptoms similar to atropine poisoning - advanced slowly reactive pupils , hot and dry skin, flushing, dry mouth and upper respiratory tract infection , fever , palpitations, cardiac arrhythmias , slow intestinal motility and retention urine , and delirium , disorientation , anxiety , hallucinations , confusion, hyperactivity , ataxia ( balance disorder ) , irritability ( petulance ) , and seizures. In severe cases, the condition may progress to stupor , unconsciousness , paralysis, cardiac arrest and respiratory depression and death.
Treatment of acute overdose includes gastric lavage and symptomatic treatment of fever , respiratory and cardiovascular disorders. As a specific antidote is administered physostigmine 1 mg intramuscularly or by slow intravenous infusion . This dose can be repeated every 20 minutes until a total of 4 mg. Since physostigmine decays very quickly , you may require additional injections every one or two chasa.Pri children and the elderly apply half this dose. The patient should be carefully observed 8 to 12 chasasled last crisis.
If omitted intake
In case of omission of a dose, the next dose should be taken as soon as possible . If the time of the next dose is near to skip the missed dose and continue taking the drug as specified mode. Do not take two doses at once.
 
Undesirable effects
Most of the side effects of treatment with biperiden result of anticholinergic effects. The most often cited dry mouth and blurred vision . These side effects are dose- dependent. Rarely occur gastrointestinal disorders ( constipation ) , drowsiness, dizziness and confusion. Very rarely in isolated cases were observed transient psychotic reactions , euphoria or disorientation, urinary retention , low blood pressure, irritability and changes in behavior.
 
storage
Store at temperatures below 25 ° C
KEEP OUT OF REACH OF CHILDREN !
Expiration date.
3 (three) years .Do not use after the expiry date stated on the packaging.
 
 
€ 15.00
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