AGAPURIN. 100 mg. 60 tablets
AGAPURIN. 100 mg. 60 tablets
Active substance :
Pentoxifylline 100 mg in 1 coated tablet.
Lactose monohydrate, corn starch , talc , magnesium stearate, colloidal silicon dioxide.
Sodium carboxymethylcellulose, granulated sugar , powdered sugar , gum arabic , talc , colloidal silicon dioxide, methyl parahydroxybenzoate , titanium dioxide (E 171).
Formulation and packaging
Coated tablets .
Content of one package :
60 coated tablets .
Marketing Authorisation Holder
Vasodilator rheological tool
The active substance belongs to the xanthine derivatives; improves blood flow in the blood vessels and increases the flexibility of erythrocytes. It inhibits platelet aggregation and decreases blood viscosity . As a result, it improves blood circulation and the blood supply of tissues with compromised blood supply .
Agapurin is intended for use in adults with impaired peripheral circulation due to reduced peripheral vascular blood flow in tissue disorders due to insufficient blood supply (eg leg ulcers ) in ischemic attack ( cerebral atherosclerosis, post-stroke conditions), poor circulation of the eye and the inner ear.
Agapurin should not use in case of hypersensitivity to the active substance and / or any of the excipients in severe haemorrhage , cerebral and retinal hemorrhage , severe bleeding disorders. In acute myocardial infarction, severe hypotension or arrhythmias , the product should be used only when absolutely necessary .
Drug administration should be avoided during pregnancy and lactation .
It is necessary to consult your doctor if you develop any of the above conditions during treatment with the drug .
Special warnings and precautions pi use
In patients with hypotension or heart disease can lower blood pressure induced by Agapurin and in rare cases , occur stenocardiac problems ( chest pain ) . Therefore , it is necessary to monitor blood pressure during treatment . Administration of high doses of the drug in patients with diabetes treated with insulin or oral antidiabetic agents, may lead to a pronounced hypoglycemia ( low blood sugar ), and thus it is necessary to adjust the dose in these patients during treatment with Agapurin .
The effect of Agapurin and other concomitantly administered medicines may affect each other . Therefore, your doctor should be informed about all medicines that you currently taking or will begin taking , whether prescribed or freely marketable. Before you begin taking any freely salable product , it is necessary to consult with your doctor. Agapurin may enhance the effects of drugs used for the treatment of hypotension and potentiate the reduction of blood pressure when used together with other medicines. Agapurin potentiate the action of anticoagulants .
Dosage and administration :
Dosage is always determined by the doctor. The customary dose in the beginning of the treatment 2 tablets 3 times a day . When significant decrease in blood pressure , as well as in longer duration of treatment , the dose was reduced to 1 tablet 3 times daily.
Method of administration
The tablets should be swallowed with a sufficient quantity of liquid and should not be chewed or crushed .
Prlodukt drug is usually well tolerated but may occur gastrointestinal complaints (nausea , vomiting, weight and stomach pain ) , dizziness, flushing ( at about 4-6 % of patients) . In rare cases, you may experience itching and skin rashes. Heart rhythm disorders , symptoms of angina ( chest pain ) and decreases in blood pressure may occur in isolated cases , especially after high doses . In rare cases, it may be observed bleeding (e.g., skin , mucous membrane or the gastrointestinal tract ) , especially in patients taking anticoagulants ( drugs that prevent the blood from clotting ) simultaneously Agapurin . In the event of adverse effects or any other unusual effects, you should consult your doctor about further use of the product.
Do not store above 25 ° C. Protect from moisture and light.
Shelf life :
Keep out of reach of children!
Do not use after the expiry date which is stated on the packaging .