AGAPURIN SR. 400 mg. 20 tablets

AGAPURIN SR. 400 mg. 20 tablets
€ 15.00
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The active substance belongs to the xanthine derivatives; improves blood flow in the blood vessels by increasing the flexibility of erythrocytes. Inhibits platelet aggregation and reduces blood viscosity, thus improving circulation and blood supply to tissues with poor blood circulation. 

AGAPURIN SR. 400 mg. 20 tablets

 
 
Active substance :
Pentoxifylline 400 mg in 1 prolonged-release tablet .
Excipients:
Core: Eudragit RS PO , Eudragit RS 100 , polyvidone K25 , talc , calcium stearate , Eudragit RL 100 , magnesium stearate.
Coating: Magnesium stearate , macrogol 6000 .
 
Formulation and packaging
Prolonged-release tablets Ingredients 1 package : 20, 50, 60 or 100 prolonged-release tablets .
 
Marketing Authorisation Holder
Zentiva

 
Pharmacotherapeutic group
Vasodilator rheological tool
 
action
The active substance belongs to the xanthine derivatives; improves blood flow in the blood vessels by increasing the flexibility of erythrocytes. Inhibits platelet aggregation and reduces blood viscosity , thus improving circulation and blood supply to tissues with poor blood circulation .
 
witness
Agapurin is intended for use in adults with impaired peripheral circulation due to reduced peripheral vascular blood flow in tissue disorders due to impaired blood supply (eg leg ulcers ) in ischemic attack ( cerebral atherosclerosis, postinsu - ltni conditions) , impaired blood circulation the eye and the inner ear.
 
Contraindications
Agapurin should not use in case of hypersensitivity to the active substance and / or any of the excipients in severe haemorrhage , cerebral and retinal hemorrhage , severe bleeding disorders. In acute myocardial infarction, severe hypotension or arrhythmias , the product should be used only when absolutely necessary .
Drug administration is not recommended during pregnancy and karmene.Neobhodimo is to consult your doctor if you develop any of the above conditions during treatment with Agapurin .
 
Special warnings and precautions for use
During treatment should be monitored blood pressure , as in patients with hypotension and unstable blood circulation blood pressure can be lowered and, in rare cases, problems arise angina ( chest pain behind the breastbone ) . Administration of high doses of drug can lead to very low blood sugar in patients with diabetes treated with insulin or oral antidiabetics . Therefore , there is a need to adjust dosages in these patients during treatment with Agapurin .
 
drug Interactions
The effect of Agapurin and other concomitantly administered medicines may affect each other . Therefore, your doctor should be informed about all medications that you currently taking or will begin taking , whether prescribed or freely marketable. Before you begin taking any freely salable product , it is necessary to consult with your doctor. Agapurin may enhance the effects of drugs used for the treatment of hypotension and potentiate the reduction of blood pressure when used together with other medicines. Agapurin potentiate the action of anticoagulants .
 
Dosage and method of administration
Dosage is always determined by the doctor. The customary dose in the beginning of the treatment is 1 tablet 2-3 times a day .
 
Method of administration
Agapurin should be taken during or after meals, with a little liquid and should not be chewed or broken .
 
overdose
In case of overdose or accidental ingestion of the medicinal product by a child should seek a doctor.
 
Undesirable effects
The medicinal product is generally well tolerated but may occur gastrointestinal complaints (nausea , vomiting, weight and stomach pain ) , dizziness, flushing ( at about 4-6 % of patients) . In rare cases, you may experience itching and redness of the skin.
Heart rhythm disorders , symptoms of angina ( chest pain behind the breastbone ) and decreases in blood pressure may occur in isolated cases , especially after high doses . Very often, it can be observed bleeding (eg skin , mucous membrane or the gastrointestinal tract ) , especially in patients taking anticoagulants Agapurin simultaneously .
In the event of adverse effects or any other unusual effects, you should consult your doctor about further use of the product.
 
storage
Do not store above 25 ° C. Protect from moisture and light. Shelf life 5 years.
 
attention
Keep out of reach of children!
Do not use after the expiry date which is stated on the packaging .
 
 
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