ADENURIC table. 120 mg. 28 table

ADENURIC table. 120 mg. 28 table
€ 75.00
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ADENURIC tablekti febuxostat contain the active ingredient and are used to treat gout, which is associated with an excess of a chemical called uric acid (urate) in the body.

ADENURIC table. 120 mg. 28 table

What ADENURIC and what it is used?

ADENURIC tablekti febuxostat contain the active ingredient and are used to treat gout, which is associated with an excess of a chemical called uric acid (urate) in the body. For some people, the amount of uric acid builds up in the blood and may become too large to remain soluble. When this happens, can form uric acid crystals in and around joints and kidneys. These crystals can cause sudden, severe pain, redness, warmth and swelling of the joints (known as a flare). If left untreated, in or around the joints can form larger deposits called tophi. These tophi can cause damage to bones and joints.
ADENURIC works by reducing uric acid levels. Maintaining low levels of uric acid by taking ADENURIC once a day, every day, stopping the formation of crystals and over time reduces symptoms. Keeping low enough uric acid levels for a sufficiently long period of time can also reduce the size of the tophus.
ADENURIC is for adults.

What should know before taking ADENURIC

Do not take ADENURIC
 If you are allergic to febuxostat or any other ingredients of this medicine (listed in Section 6).

Warnings and Precautions

Talk to your doctor before taking ADENURIC:
  If you have or have had heart failure or heart problems
  If you have or have had kidney disease and / or serious allergic reaction to allopurinol (a drug used to treat gout)
  If you have or have had liver disease or liver deviation indicators
  If you are being treated for high uric acid levels as a result of cancer or syndrome-Carrion Nihat (a rare hereditary disease in which there is too much uric acid in the blood)
  If you have thyroid problems.
If you experience allergic reactions to ADENURIC, stop taking this medication (see also Section 4)
Possible symptoms of an allergic reaction may include:
Rash, including serious forms (eg, blisters, nodules, scaly rash), itching
 Swelling of the limbs or face
 Difficulty breathing
 But also serious life-threatening allergies to heart failure or circulation.
Your doctor may decide to stop treatment for all ADENURIC.
Have been reported rarely potentsialno life-threatening rash (Stevens-Johnson syndrome) when taking ADENURIC, occurring on the body, first as red spots round or oval spots, often with bubble in the center. You can also include sores in the mouth, throat, nose, genitals and conjunctivitis (red and swollen eyes). The rash can develop into blisters or peeling skin covering large areas.
If you experience Stevens-Johnson syndrome with the use of febuxostat should never start again ADENURIC. If you experience any skin rash or symptoms, consult a doctor immediately and say that you are taking this medicine.
If you currently have a flare (sudden onset of severe pain, tenderness, redness, warmth and swelling in a joint), wait a gout attack to subside before the first treatment with ADENURIC.
For some people, gout attacks may be increased at the start of treatment with certain drugs that control uric acid. Not all get aggravated, but you might have a flare even if you take ADENURIC, especially during the first weeks or months. It is important to continue taking ADENURIC even if you have a flare, as ADENURIC still working to lower uric acid. Over time, gout attacks will occur more often and be less painful if you keep taking ADENURIC every day.
Your doctor will often prescribe other medicines if needed to prevent or treat symptoms of seizures (such as pain and swelling of the joints).
Your doctor may ask you to have blood tests to check that your liver is working properly.
Children and adolescents
Do not give this medicine to children under 18 godinshna age because safety and efficacy have not been established.
Other medicines and ADENURIC
Tell your doctor or pharmacist if you are taking, have recently taken or may take other medicines, including medicines obtained without a prescription.
It is particularly important to tell your doctor or pharmacist if you are taking medicines containing any of these substances as they may interact with ADENURIC and your doctor may take appropriate measures:
  Mercaptopurine (used to treat cancer)
  Azathioprine (used to reduce immune response)
  Theophylline (used to treat asthma)
Pregnancy and lactation
It is not known if ADENURIC may harm your unborn child. ADENURIC should not be used during pregnancy. It is not known if ADENURIC may pass into breast milk. You should not take ADENURIC, if you are breastfeeding or plan to breastfeed.
If you are pregnant or nursing, you think you may be pregnant or plan to become pregnant, ask your doctor or pharmacist before taking this medicine.
Driving and operating machinery
Be aware that you may experience dizziness, drowsiness, blurred vision, numbness or tingling sensation during treatment and should not drive or operate machinery if affected.
ADENURIC lactose
ADENURIC tablets contain lactose (a sugar). If you have been told you have an intolerance to some sugars, contact your doctor before taking this medicine.


Always take this medicine exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.
ADENURIC is available as a 80 mg tablet or tablet of 120 mg. Your doctor will prescribe the most appropriate dose for you.
  The usual dose is one tablet daily. On the back of the blister pack marked the days of the week to help you check whether you take one dose each day.
  The tablets should be taken orally and can be taken with or without food
Continue to take ADENURIC every day, even when not experiencing a flare or exacerbation.
If you take more ADENURIC than
In case of accidental overdose, ask your doctor what to do or contact your nearest hospital casualty department and emergency assistance.
If you forget to take ADENURIC
If you miss a dose ADENURIC, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and take the next dose at the usual time. Do not take a double dose to make up for a missed dose.
If you stop taking ADENURIC
Do not stop taking ADENURIC without the advice of your doctor even if you feel better. If you stop taking ADENURIC uric acid levels may begin to rise and your symptoms may worsen due to the formation of new urate crystals in and around joints and kidneys.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

 Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking this medicine and contact your doctor or go to the nearest emergency department if you experience the following rare side effects (may affect up to 1 in 1,000 people), because you can follow a serious allergic reaction:
  anaphylactic reactions, drug hypersensitivity (see also section 2. "Warnings and Precautions")
  potentially life-threatening skin rashes characterized by blistering and peeling of the skin and the inner surface of body cavities, eg. mouth and genitalia, boleznini mouth ulcers and / or genitalniite accompanied by fever, sore throat and fatigue (Stevens-Johnson syndrome) (see section 2)
  Generalized rash
Common side effects (may affect up to 1 in 10 people) are:
 abnormal liver test results
  rash (including various types of rashes, please see below in the sections "infrequent" and "frequent"
  strengthening of gout symptoms
  localized swelling due to fluid retention in the tissues (edema)
Below are listed other adverse reactions not mentioned above.
Uncommon side effects (may affect up to 1 in 100 people) are:
  decreased appetite, change in blood sugar levels (diabetes), whose symptoms can be excessive thirst, increased levels of blood lipids, increased weight
  loss of sex drive
 trouble sleeping, drowsiness
  dizziness, numbness, tingling, decreased, or altered sense of touch (hypoaesthesia, paraesthesia and hemiparesis), reduced or altered taste (hyposmia)
  abnormal electrocardiogram, an irregular heartbeat, palpitations
  flushing or blushing (eg redness of the face or neck), increased blood pressure
   cough, shortness of breath, pain or discomfort in the chest, inflammation of the nasal passages and / or throat (upper respiratory tract), bronchitis
  dry mouth, abdominal pain / discomfort or gas, heartburn / indigestion, constipation, frequent stools, vomiting, stomach discomfort
  itching, hives, skin inflammation or skin discoloration, tiny red or purple spots on the skin, small, flat red spots on the skin, flat red areas on the skin, covered with small confluent bumps, rash, areas of redness and spots skin and other skin diseases
  muscle cramps, muscle weakness, pain in muscles / joints, bursitis or arthritis (inflammation of joints, usually accompanied by pain, swelling and / or stiffness), pain in extremity, back pain, muscle spasms
  blood in the urine, excessive urination, abnormal urine tests for (increased protein in the urine), reduced ability of the kidneys to function properly
  fatigue, chest pain, chest discomfort
  stones in the gallbladder or bile ducts (cholelithiasis)
  increased levels of thyroid stimulating hormone (TSH) in the blood
  changes in blood chemistry or amount of blood cells or platelets (abnormal results in blood tests)
  kidney stones
  erectile dysfunction
Rare side effects (may affect up to 1 in 1,000 people) are:
  muscle damage, a condition which in rare cases can be serious. This can cause muscle problems, especially if at the same time you feel unwell or have a fever, this may be caused by abnormal muscle breakdown. Contact your doctor immediately if pochuvstavate muscle pain, tenderness or weakness
  Severe swelling of the deeper layers of the skin, especially around the lips, eyes, genitals, hands, feet or tongue with possible sudden shortness of breath
  skin redness (erythema), rash different types (eg, itchy, white spots, blisters with pus-filled blisters and sloughing of the skin rash similar to smallpox)
  Ringing in the ears
  blurred vision, change in vision
  sores in the mouth
  inflammation of the pancreas: common symptoms are abdominal pain, nausea and porashtane
  increased sweating
  reduced weight, increased appetite, uncontrolled loss of appetite (anorexia)
  stiffness in the muscles and / or joints
  abnormally low blood cell counts (red or white blood cells or platelets)
  urgent urination
  changing or reducing the amount of urine, resulting in inflammation of the kidney (tubulointerstitial nephritis)
  inflammation of the liver (hepatitis)
  yellowing of the skin (jaundice)
If you experience any side effects tell your doctor or pharmacist. This includes all listed in this leaflet.

 How to store ADENURIC

 Keep out of reach of children.
 Do not use this medicine after the expiry date stated on the carton and on the foil blister after "EXP". The expiry date refers to the last day of that month.
 This medicine does not require any special storage conditions.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

 Package Contents and other information



The active substance is febuxostat.
Each tablet contains 80 mg or 120 mg of febuxostat.
The other ingredients are:
Tablet core: lactose monohydrate, microcrystalline cellulose, magnesium stearate, hydroxypropyl cellulose, croscarmellose sodium, silica colloidal hydrated.
Film coating: Opadry II 85F42129 containing yellow: polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc, iron oxide yellow (E172)
ADENURIC looks like and contents of pack
ADENURIC tablets are pale yellow to yellow and capsule shaped.
€ 75.00
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